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Singapore Clinical Trial: A randomized, placebo-controlled, participant- and investigator-blinded study to evaluate the efficacy in reducing atrial fibrillation burden (AFB) as well as the safety, tolerability, and pharmacokinetics of oral PKN605 in participants with atrial fibrillation

Singapore, April 26 -- The Health Sciences Authority received information related to the study titled 'A randomized, placebo-controlled, participant- and investigator-blinded study to evaluate the eff... Read More


Singapore Clinical Trial: A Phase 2/3 Randomized Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab Adizutecan in Combination with Osimertinib as First-Line Treatment in Patients with Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

Singapore, April 26 -- The Health Sciences Authority received information related to the study titled 'A Phase 2/3 Randomized Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab ... Read More


Singapore Clinical Trial: A Study to Evaluate the Effect of Fasting Duration and Temporary Withholding of Tirzepatide on Retained Gastric Contents Using Gastric Ultrasound in Participants with Type 2 Diabetes Mellitus and Participants with Overweight or Obesity without Type 2 Diabetes Mellitus.

Singapore, April 26 -- The Health Sciences Authority received information related to the study titled 'A Study to Evaluate the Effect of Fasting Duration and Temporary Withholding of Tirzepatide on Re... Read More


Singapore Clinical Trial: A Phase 1/2 Open-Label, Umbrella Platform Design Study of Investigational Agents in Combination With Pembrolizumab (MK-3475) With or Without Chemotherapy in Participants With 1L Locally Advanced Unresectable/Metastatic Esophageal Cancer: KEYMAKER-U06 Substudy 06E

Singapore, April 26 -- The Health Sciences Authority received information related to the study titled 'A Phase 1/2 Open-Label, Umbrella Platform Design Study of Investigational Agents in Combination W... Read More


Clinical Trial: Effects of bridge exercise on gluteus maximus muscle function: comparison with single-leg wall squat (Japan)

Tokyo, April 26 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061373) titled 'A study on changes in gluteus maximus muscle function induced by bridge ex... Read More


Clinical Trial: Long-Term Safety Evaluation and Exploratory Assessment of Anti-Fatigue Effects of Continuous Intake of Food Containing Orotic Acid - A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial - (Japan)

Tokyo, April 26 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061228) titled 'Long-Term Safety Evaluation and Exploratory Assessment of Anti-Fatigue Eff... Read More


Clinical Trial: The effect of visual attention training on improving ADL ability in patients with subacute stroke: A pilot randomized controlled trial (Japan)

Tokyo, April 27 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061380) titled 'A study investigating whether training to improve visual attention can hel... Read More


Clinical Trial: An exploratory study of the effects of a foot bone-strengthening program on bone-related indicators, toe muscle strength, foot function, physical function, and health-related indicators, and the associations among these measures in male and female participants (Japan)

Tokyo, April 27 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061377) titled 'Exploratory study on the effects of a foot bone-strengthening program on b... Read More


Clinical Trial: An interventional study examining the effects and correlations of exercise and health support programs including the BONE program on physical function, immune function, cognitive function, posture, quality of life, and comprehensive health indicators in middle-aged and older adult women (Japan)

Tokyo, April 27 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061376) titled 'Effects and associations of exercise and health support programs including... Read More


Clinical Trial: A Randomized Controlled Trial on the Use of AI Avatars for Pre-Discharge Patient Education: Effects on Workflow Efficiency, Patient Understanding, and Satisfaction (Japan)

Tokyo, April 27 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060705) titled 'A study to examine whether AI avatar-based pre-discharge explanations impr... Read More